Does clindamycin have anaerobic coverage?
Like cloxacillin and the cephalosporins, clindamycin possesses activity against Staphylococcus aureus. It has broader anaerobic coverage than most cephalosporins, but has virtually no activity against aerobic Gram-negative bacteria.
What does clindamycin cover?
Clindamycin is an antibiotic used for treatment of a number of bacterial infections, including bone or joint infections, pelvic inflammatory disease, strep throat, pneumonia, middle ear infections, and endocarditis. It can also be used to treat acne, and some cases of methicillin-resistant Staphylococcus aureus (MRSA).
Does cefuroxime have anaerobic coverage?
At 16 microgram/ml, cefuroxime inhibited 70% of all anaerobic bacteria, but it was ineffective against 64% of B. fragilis strains tested.
What anaerobes does clindamycin cover?
Clindamycin is a lincosamide antibiotic that has been approved by the US Food and Drug Administration for the treatment of anaerobic, streptococcal, and staphylococcal infections.
What type of bacteria does clindamycin cover?
Clindamycin is an antibiotic used for treating serious infections. It is effective again several types of bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, Staphylococcus epidermidis, and Propionibacterium acnes. It reduces growth of bacteria by interfering with their ability to make proteins.
Does amoxicillin have anaerobic coverage?
Amoxicillin is similar to penicillin in its spectrum of coverage against oral pathogens. The addition of a beta-lactamase inhibitor (such as clavulanic acid) makes amoxicillin active against most aerobic and anaerobic BLPB.
What types of infections does clindamycin treat?
The Food and Drug Administration (FDA) have approved clindamycin to treat:
- blood infections.
- septicemia, which is blood poisoning.
- abdominal infections.
- lung infections.
- infections of the female reproductive tract.
- bone and joint infections.
- skin infections.
Does Ceftin cover anaerobes?
Cefuroxime showed high activity against gram-positive anaerobe, except some Clostridium. Against gram-negative anaerobes, cefuroxime was equally active as cefoxitin and more active than other cephalosporins. For Bacteroides fragilis, cefuroxime showed stronger antibacterial activity at decreased inoculum size.
Do cephalosporins cover anaerobes?
The third-generation cephalosporins have an increased spectrum of activity against gram-negative bacteria, moderate activity against anaerobic bacteria, and reduced anti-gram-positive activity as compared with earlier cephalosporins.
What bacteria is clindamycin resistant?
Antimicrobial Activity Most aerobic gram-negative bacteria, such as Pseudomonas spp and H. influenzae, are inherently resistant to clindamycin because of poor permeability of the cellular outer envelope to the drug. An exception is Capnocytophaga canimorsus, which is highly susceptible to clindamycin.
What is the antibiotic activity of cefpodoxime proxetil?
The antimicrobial activity of cefpodoxime, the active metabolite of the new cephalosporin ester cefpodoxime proxetil, in comparison to cefixime, cefotiam, cefuroxime, and cefotaxime was determined against a broad spectrum of freshly isolated gram-positive and gram-negative bacterial strains.
How many mg of MIC does Cefpodoxime have?
The MICs of cefpodoxime and those of the other cephalosporins were less than 2 mg/l for greater than or equal to 90% of the strains of Staphylococcus aureus and Staphylococcus epidermidis, with the exception of cefixime which had no activity with MICs below 8 mg/l against these bacteria.
What kind of bacteria are resistant to cefpodoxime?
Pseudomonas spp., Acinetobacter spp., and Enterococcus spp. were resistant to cefpodoxime.
Which is the second generation cephalosporin Lorabid or Cefaclor?
Structurally, loracarbef (Lorabid) is a carbacephem rather than a cephalosporin. However, loracarbef is so similar to cefaclor in spectrum of antimicrobial activity and side effects that it is usually listed as a second-generation cephalosporin.