What is a normal Anticardiolipin level?
What is a normal Anticardiolipin level?
Anticardiolipin Antibody (IgG, IgM, IgA)
| General Information | |
|---|---|
| Normal Range | < 20 CU for IgG, IgM and IgA |
| Reflexive Testing | None |
| Associated Testing | Antiphospholipid Syndrome Criteria Panel, Lupus Anticoagulant Screen |
| Special Instructions & Forms |
What does high anticardiolipin antibody mean?
Moderately or very high levels of anticardiolipin antibodies that persist for 12 weeks or more indicate a continued presence of these autoantibodies and an increased risk of abnormal clots and miscarriages.
What does a high cardiolipin antibody test mean?
A positive result means that cardiolipin antibody was detected in the blood. As mentioned earlier, the presence of cardiolipin antibodies may indicate several diseases, such as: Syphilis. Antiphospholipid syndrome (APS) Systemic lupus erythematosus (SLE)
What is a glycoprotein and what does it do?
Glycoproteins are molecules that comprise protein and carbohydrate chains that are involved in many physiological functions including immunity. Many viruses have glycoproteins that help them enter bodily cells, but can also serve to be important therapeutic or preventative targets.
What do antiphospholipid antibodies do?
Antiphospholipid antibodies are a group of immune proteins (antibodies) that the body mistakenly produces against itself in an autoimmune response to phospholipids. Tests can detect these autoantibodies that bind to phospholipids and, in a way that is not well understood, increase the risk of excessive blood clotting.
When is beta 2 glycoprotein 1 IgM antibody high?
In the event that the level of beta 2 glycoprotein 1 IgM antibody is high in the test results done after a gap of 12 weeks, it is almost confirmed the patient is a victim of APS. To make it a clear and confirmed diagnosis of APS, healthcare providers align the tests of blood test results along with clinical symptoms.
What is beta 2 glycoprotein 1 in blood?
Beta-2 glycoprotein 1 antibody is an autoantibody that is associated with inappropriate blood clotting. This test detects and measures beta-2 glycoprotein 1 antibodies in the blood.
Can a negative beta 2 glycoprotein 1 result indicate APS?
It is important to know that just one positive beta-2 glycoprotein 1 antibody result does not point to the diagnosis of APS. Similarly, a negative test result does not mean there is no antibody development. It just shows the presence or absence of antibodies during the period of the test.
Which is more sensitive Beta 2 or cardiolipin 1?
However, beta 2 glycoprotein 1 antibodies have been reported to be more specific (but less sensitive) than cardiolipin antibodies for the diagnosis of APS. Laboratory tests can detect three different classes of these autoantibodies: IgG, IgM, and IgA.