What is bio4 bone graft?
BIO. 4® BIO4® is a viable bone matrix containing endogenous bone forming cells including mesenchymal stem cells, osteoprogenitor cells, osteoblasts, osteoinductive and angiogenic growth factors.
What components of bone are included in bio4?
BIO4 possesses all four characteristics involved in bone repair and regeneration: osteoconductive, osteoinductive, osteogenic, and angiogenic.
Is DBM synthetic?
Bone graft substitutes—these are synthetic or a manipulated type of naturally-occurring product. Demineralized Bone Matrix (DBM)—allograft cadaver bone is manipulated (demineralized) to extract the proteins that stimulate/promote bone formation. DBM can be found is various forms like chips, gel, putty or powder.
What is vitoss?
Vitoss is a highly porous beta-tricalcium phosphate (up to 90% porous)1 with clinical research demonstrating efficacy in a variety of anatomical locations. 2. Vitoss can be hydrated with bone marrow aspirate (BMA), whole blood, or saline.
What is Trinity Elite allograft?
Trinity Elite is a cryopreserved, viable cellular allograft containing cancellous bone and demineralized cortical bone designed for surgical use by qualified health care professionals. Processed human bone has been used in a variety of surgical applications and in combination with prosthetic devices.
Is bio4 human tissue?
Our current Biosurgery products are derived from human tissue donated for transplant. Grafix is derived from human placental tissue, and BIO4 and Cartiform are derived from donated human cadaveric tissue.
What is cellular allograft?
OSTEOCEL ALLOGRAFT CELLULAR BONE GRAFT Osteocel is a comprehensive bone graft developed to mimic your own bone autograft. These bone-forming cells are naturally present in our bodies and are essential for bone tissue formation and healing. Osteocel technology preserves the live bone-forming cells in donor tissue.
Is demineralized bone matrix synthetic?
Demineralized bone matrix is osteoconductive but does not provide structural support. These synthetic bone graft materials range from those with little or no osteoinductive capacity, such as calcium sulfate, to highly osteoinductive materials, such as BMP-2 and BMP-7.
What is DBM made of?
Demineralized bone matrix (DBM) is an osteoconductive scaffold that is manufactured by acid extraction of allograft bone. While it provides no structural support, it contains noncollagenous proteins, osteoinductive growth factors, and type I collagen. DBM is a mixture of BMPs and immunogenic, noninductive proteins.