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28/12/2019

What is malignant effusion?

What is malignant effusion?

A malignant pleural effusion (MPE) is the build up of fluid and cancer cells that collects between the chest wall and the lung. This can cause you to feel short of breath and/or have chest discomfort. It is a fairly common complication in a number of different cancers.

What does exudative pleural effusion mean?

Exudative. This forms from extra liquid, protein, blood, inflammatory cells or sometimes bacteria that leak across damaged blood vessels into the pleura. You may need to get it drained, depending on its size and how much inflammation there is. The causes of this type include pneumonia and lung cancer.

Can you survive malignant pleural effusion?

Development of a malignant pleural effusion is associated with a very poor prognosis, with median survival of 4 months and mean survival of less than 1 year. The most common associated malignancy in men is lung cancer.

How does tuberculous pleural effusion affect lung function?

Tuberculous effusion is a common disease entity with a spectrum of presentations from a largely benign effusion, which resolves completely, to a complicated effusion with loculations, pleural thickening and even frank empyema, all of which may have a lasting effect on lung function. The pathogenesis …

How can you tell if you have pleural tuberculosis?

The diagnosis is simple if M. tuberculosis is detected in sputum, pleural fluid or biopsy specimens, and the recent advent of liquid medium culture techniques has increased the microbiological yield dramatically.

Why is tuberculous pleuritis more common in young males?

It may be commoner in young males and afflicted patients tend to be younger than those who get pulmonary tuberculosis 2. In most cases, tuberculous pleuritis is believed to stem from either rupture of a subpleural granuloma into the pleural space or dissemination of the mycobacteria via pleural lymphatics.

When to use a pleural biopsy for TB?

Pleural biopsy for liquid culture and susceptibility testing must also be considered where the prevalence of drug resistant TB is high. Treatment regimens are identical to those administered for pulmonary TB. Initial pleural drainage may have a role in symptom relief and in hastening the resolution of the effusion.