What is normal range for LDL levels?
LDL cholesterol levels should be less than 100 mg/dL. Levels of 100 to 129 mg/dL are acceptable for people with no health issues but may be of more concern for those with heart disease or heart disease risk factors. A reading of 130 to 159 mg/dL is borderline high and 160 to 189 mg/dL is high.
What is the optimal level of LDL?
It is extremely important for everyone — men and women of every age, with or without known heart disease — to have a low LDL cholesterol level. The optimal guideline level of LDL cholesterol is less than 100 mg/dl.
At what LDL do you start statins?
For most patients with an LDL-C >100 mg/dL (2.59 mmol/L) and a 10-year cardiovascular disease (CVD) risk of 10 percent or greater, we initiate statin therapy. This approach may differ in specific populations, such as the very young, the very old, and those with diabetes.
What should your LDL level be in your blood?
In 1986, a “desirable” blood level of low-density lipoprotein (LDL, the so-called bad cholesterol) was 130 milligrams per deciliter (mg/dL). Today, information from medical anthropologists and some high-powered clinical trials suggests the new “desirable” should be half that.
Where are the LDL receptors located in the body?
LDL receptors are on the outside of many different cells. When low density lipoproteins, sometimes referred to as the “bad” cholesterol, circulate through the body, the LDL receptors pick them up and get them into the cell.
What happens if the LDL receptor is malfunctioned?
Malfunctioning LDL receptors can cause a buildup of cholesterol in the arteries. The primary job of LDL receptors is to keep the amount of cholesterol in the blood at a normal level. LDL receptors are on the outside of many different cells.
What does the LDLR gene do in the body?
The LDLR gene provides instructions for making a protein called the low-density lipoprotein receptor. This receptor binds to particles called low-density lipoproteins (LDLs), which are the primary carriers of cholesterol in the blood.