What is the difference between mismatch repair a nucleotide excision repair?
What is the difference between mismatch repair and nucleotide excision repair? In mismatch repair, one nucleotide is replaced, whereas in nucleotide excision repair several nucleotides are replaced. You just studied 29 terms!
What is the difference between BER and NER?
NER and BER are two types of DNA excision repair processes found in cells. BER is able to repair small damages caused endogenously while NER is able to repair damage regions up to 30 base pair length caused mostly by exogenously. This is the difference between base excision repair and nucleotide excision.
What is the mismatch repair system?
DNA mismatch repair (MMR) is a system for recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases that can arise during DNA replication and recombination, as well as repairing some forms of DNA damage.
What is the process of nucleotide excision repair?
Nucleotide excision repair (NER) is the process by which helix-distorting DNA lesions and bulky adducts, such as those induced by UV (ultraviolet light), cisplatin, cigarette smoke, and aflatoxin, are removed from the genome.
What is the difference between base excision and nucleotide excision repair?
Base excision repair (BER) is a DNA repair system occurs in cells. Nucleotide excision repair (NER) is another type of DNA repair system found in cells.
How is a mismatch repaired in a DNA strand?
Mismatch repair. A mismatch is detected in newly synthesized DNA. The new DNA strand is cut, and a patch of DNA containing the mispaired nucleotide and its neighbors is removed. The missing patch is replaced with correct nucleotides by a DNA polymerase. A DNA ligase seals the remaining gap in the DNA backbone.
How is DNA damage repaired in the cell?
At least five major DNA repair pathways—base excision repair (BER), nucleotide excision repair (NER), mismatch repair (MMR), homologous recombination (HR) and non-homologous end joining (NHEJ)—are active throughout different stages of the cell cycle, allowing the cells to repair the DNA damage.
What are the different types of DNA repair?
Regardless of these damages, the cell initiates a highly organized cascade repair mechanism called DNA damage responses. Several DNA repair systems have been identified in the cellular system; these are known as Base excision repair (BER), Mismatch repair (MMR), Nucleotide excision repair (NER), Double strand break repair.