How much benzocaine is lethal?

How much benzocaine is lethal?

Poisindex® states that the threshold toxic dose for benzocaine is 22-40 mg/kg.

What are the side effects of benzocaine?

dizziness, breathing problems, fast heart rate, and. gray or bluish colored skin (rare but serious side effects of benzocaine);…Common side effects of Americaine (benzocaine) include application site reactions such as:

• stinging,
• burning, or.
• itching,
• skin tenderness or.
• redness, or.
• dry white flakes.

What does benzocaine do to the body?

It works by blocking nerve signals in your body. Benzocaine topical is used to reduce pain or discomfort caused by minor skin irritations, sore throat, sunburn, vaginal or rectal irritation, ingrown toenails, hemorrhoids, and many other sources of minor pain on a surface of the body.

Does benzocaine make you feel high?

Some people may also smoke or snort benzocaine by itself trying to replicate a cocaine high. However, benzocaine is far from a safer high. Because its effects are much weaker, people may use it in higher doses, which can lead to a fast or slow heartbeat, stopped breathing, or seizures.

Can too much Orajel be bad?

In fact, the agency concluded Baby Orajel and other over-the-counter benzocaine products marketed for teething pain can on occasions lead to serious —and sometimes fatal — methemoglobinemia.

What are the chances of getting methemoglobinemia from Orajel?

001). Conclusions and relevance: The overall prevalence of methemoglobinemia is low at 0.035%; however, an increased risk was seen in hospitalized patients and with benzocaine-based anesthetics.

How long do the effects of benzocaine last?

C Other Local Anesthetics. Benzocaine is a water-insoluble ester-type local anesthetic agent that is mainly useful for topical application. The onset of action is rapid (<1 minute), and the effective duration is 5 to 10 minutes.

Is benzocaine a drug?

Benzocaine is a topical anesthetic contained in some marketed over-the-counter (OTC) oral drug products intended to relieve pain from a variety of conditions such as sore throats, canker sores, and irritation of the mouth and gums.

Is it illegal to have lidocaine?

There is no confusion – lidocaine is legal to own, sell, and use.

How safe is benzocaine?

Benzocaine Safety Information Benzocaine can cause a serious condition in which the amount of oxygen carried through the blood is greatly reduced. This condition, called methemoglobinemia, is life-threatening and can result in death.

Who is most at risk for benzocaine toxicity?

Drug Warning. Infants and the elderly were more likely to develop toxic methemoglobinemia after benzocaine exposure. Other risk factors included genetic reductase deficiencies, exposure to high doses of anesthetic, and presence of denuded skin and mucous membranes. Because of the potential for severe complications,…

What can benzocaine be used for over the counter?

*The cases were reported to the FDA Adverse Event Reporting System (FAERS). Benzocaine is a topical anesthetic contained in some marketed over-the-counter (OTC) oral drug products intended to relieve pain from a variety of conditions such as sore throats, canker sores, and irritation of the mouth and gums.

Can a 2 year old take benzocaine over the counter?

[ 05-23-2018 ] The U.S. Food and Drug Administration (FDA) is warning that over-the-counter (OTC) oral drug products containing benzocaine should not be used to treat infants and children younger than 2 years.

What are the side effects of using benzocaine?

These include pale, gray or blue-colored skin, lips, and nail beds; shortness of breath; fatigue; confusion; headache; lightheadedness; and fast heart rate. Signs and symptoms of methemoglobinemia may appear within minutes to one to two hours after using benzocaine.