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13/02/2020

Is hemoglobin C trait the same as sickle cell trait?

Is hemoglobin C trait the same as sickle cell trait?

Hemoglobin C trait is common and can occur in any race or ethnicity. It is most common in individuals of African American of West African descent. You may have heard of sickle cell trait before, while not exactly the same, sickle cell trait and hemoglobin C trait are similar.

Is hemoglobin C sickle cell?

Hemoglobin sickle C disease is a “mild” form of sickle cell anemia. Your child’s red blood cells (RBC’s) contain two abnormal hemoglobins called hemoglobin S and hemoglobin C. Hemoglobin is the substance in the RBC’s which carries oxygen to all parts of the body.

What does it mean to have the hemoglobin C trait?

Hemoglobin C trait (hemoglobin C carrier) occurs when a person inherits one gene for hemoglobin C and one gene for hemoglobin A. Individuals with hemoglobin C trait are NOT at risk to develop sickle cell disease or hemoglobin C disease. They generally do NOT have any medical problems and lead normal lives.

Can CC genotype live long?

Hemoglobin C disease (Hb CC) is a mild disorder that generally does not cause any symptoms and is associated with a normal life expectancy.

Is CC sickle cell?

Hemoglobin C disease is not a form of sickle cell disease. People who have hemoglobin C disease have red blood cells that contain mostly hemoglobin C. Too much hemoglobin C can reduce the number and size of red blood cells in your body, causing mild anemia.

What does CC genotype mean?

If a person inherits a gene for Hemoglobin C from both parents (CC), that person will have Hemoglobin C disease. This disease may produce mild to moderate anemia, jaundice, enlarged spleen and gallstones.

How do you treat hemoglobin C?

Treatment. Although hemoglobin C disease is a chronic condition, it usually doesn’t require any treatment. The anemia that develops is mild and rarely interferes with everyday life. Neither children nor adults need any special therapy, vitamins, or iron supplements to treat hemoglobin C disease.

What is the best blood genotype?

Health Tips

  • Types of Genotype. The genotypes in humans are AA, AS, AC, SS. They refer to the hemoglobin gene constituents on the red blood cells.
  • Compatible genotypes for marriage are: AA marries an AA. That’s the best compatible.
  • Solution. The only thing that can change the genotype is the bone marrow transplant (BMT).

Is SC genotype A Sickler?

Hemoglobin SC disease is the second most common type of sickle cell disease. It occurs when you inherit the Hb C gene from one parent and the Hb S gene from the other. Individuals with Hb SC have similar symptoms to individuals with Hb SS. However, the anemia is less severe.

What is SC and CC in genotype?

A third allele (C) results in the following genotypes and phenotypes: AC is normal but susceptible, SC has mild anemia and CC is normal and resistant to malaria. The following approximate fitnesses have been assigned to these genotypes: Genotype.

What is a hemoglobin C test?

Hemoglobin C is a blood test used to find out if you have hemoglobin C disease, a blood disorder passed on to you from your parents. It causes your red blood cells to have hemoglobin C instead of the hemoglobin A found in most people.

How do you get sickle cell?

Sickle cell disease occurs when a person inherits two abnormal copies of the haemoglobin gene, one from each parent. This gene occurs in chromosome 11. Several subtypes exist, depending on the exact mutation in each haemoglobin gene.

How is sickle cell anemia diagnosed?

Sickle cell anemia can be diagnosed through a blood test. The blood test check for hemoglobin S – the defective form of hemoglobin make you get sickle cell anemia. Treatments of the disease include antibiotics, blood transfusion and bone marrow transplant, as well as other treatments for complications resulting from sickle cell anemia.

How is sickle cell anemia inherited?

Sickle cell anemia is inherited in an autosomal recessive manner. This means that the disease develops when someone receives two copies of the mutated HBB gene: one from the mother and one from the father. A person with just one copy of the mutated gene is said to have the sickle cell trait.