What is AMACR deficiency?

What is AMACR deficiency?

Alpha-methylacyl-CoA racemase (AMACR) deficiency is a disorder that causes a variety of neurological problems that begin in adulthood and slowly get worse. People with AMACR deficiency may have a gradual loss in intellectual functioning (cognitive decline), seizures, and migraines.

What is prostatic acinar adenocarcinoma?

Acinar adenocarcinoma Adenocarcinomas are cancers that develop in the gland cells that line the prostate gland. They are the most common type of prostate cancer. Nearly everyone with prostate cancer has this type.

Is prostate adenocarcinoma malignant?

Adenocarcinoma of the prostate is malignant, however many types grow extremely slowly, and so are unlikely to spread before a man dies of other causes.

What is p63 a marker for?

p63 is also a marker for squamous cell carcinoma. Recently, it was found that all p53 family members are involved in regulating the process of muscle differentiation through the retinoblastoma (RB) protein.

What is p63 on a pathology report?

Tumor protein 63 (p63) is a transcription factor of the p53 gene family involved in differentiation of several tissues including squamous epithelium. p63 immunohistochemistry is broadly used for tumor classification but published data on its expression in cancer is conflicting.

What causes iron deficiency anemia in older adults?

The depletion of iron stores may result from blood loss, decreased intake, impaired absorption, or increased demand. Iron-deficiency anemia could arise from occult gastrointestinal bleeding. Adults older than 50 years of age with iron-deficiency anemia and gastrointestinal bleeding need to be evaluated for malignancy.

What should serum ferritin level be for iron deficiency anemia?

The following diagnostic approach is recommended in patients with anemia and is outlined in Figure 1. 2, 6 – 11 A serum ferritin level should be obtained in patients with anemia and a mean corpuscular volume less than 95 μm 3.

What happens to a child with iron deficiency anemia?

Growth problems. In infants and children, severe iron deficiency can lead to anemia as well as delayed growth and development. Additionally, iron deficiency anemia is associated with an increased susceptibility to infections. You can reduce your risk of iron deficiency anemia by choosing iron-rich foods.

What are the results of an iron deficiency smear?

In an individual who is anemic from iron deficiency, these tests usually show the following results: The peripheral smear or blood slide may show small, oval-shaped cells with pale centers.