What is Livedoid vasculitis?

What is Livedoid vasculitis?

Livedoid vasculitis, otherwise known as segmental hyalinizing vasculitis or livedo reticularis with summer ulceration, is a chronic disease with lesions affecting the feet and lower legs.

Can cryoglobulinemia be cured?

The mainstay of treatment is corticosteroids with or without other medications depending on the affected organ and the extent of involvement. Another form of treatment decreases the amount of cryoglobulins in the blood.

Is Livedo Reticularis serious?

Livedo reticularis itself is relatively benign. However, thromboembolic disease due to associated conditions such as antiphospholipid syndrome may lead to serious arterial events, including the death of the patient.

What is life expectancy with vasculitis?

Mean survival time was 126.6 months (95% confidence interval [CI] = 104.5 to 148.6) limited to 154.6 months for the longest-surviving patient.

What is the lifespan of someone with vasculitis?

Since 2010, the mean survival changed from 99.4 to 126.6 months, more than two years. Patients with higher disease activity at diagnosis, determined by the Birmingham Vasculitis Activity Score, also were found to have a poorer prognosis.

Is there a cure for livedoid vasculopathy?

While ruling out the various disease states that have been associated with livedoid vasculopathy, physicians can offer a number of therapies that have been very helpful in reducing pain and ulceration. Instituting treatment as soon as possible is best.

What does livedoid vasculopathy mean in medical terms?

Livedoid vasculopathy is a rare, chronic vascular disorder characterised by persistent painful ulceration of the lower extremities. The condition occurs chiefly but not exclusively on the lower leg or foot. Livedoid vasculopathy was also known as ‘ livedo vasculitis ’, ‘livedoid vasculitis’ and ‘livedo reticularis with summer ulceration’.

Is there any treatment for atrophie blanche and livedoid vasculopathy?

[ 50] Several reports have noted that intravenous immunoglobulin (IVIG) can be useful in treating atrophie blanche and livedoid vasculopathy, but this remains an experimental treatment. [ 51] Bounfour et al treated five patients with livedoid vasculopathy with IVIG and four patients experienced successful outcomes. [ 52]

How is pentoxifylline used to treat Livedoid vasculopathy?

Pentoxifylline is believed to enhance the blood flow in the capillaries. The blood flow enhancement is attributed to making red blood cells more flexible and thereby reducing viscosity. [35] In 2003, Hairston et al [36] described treatment of livedoid vasculopathy with low molecular weight heparin (LMWH).