What is the structure of dextran?
Is dextran structural polysaccharide?
Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, which have a linear backbone of α-linked d-glucopyranosyl repeating units. Three classes of dextrans can be differentiated by their structural features.
What type of solution is dextran?
Dextran is a high molecular weight, inert, water soluble polymer that has been used in a wide variety of bio-medical applications.
What is dextran in bacteria?
Dextrans are chemical sugars obtained from bacteria. These are rapidly degraded enzymes known as dextranases. This enzyme is profoundly available in bacteroides. It has a linear backbone polymer of polysaccharide.
Which is a structural polysaccharide?
Cellulose and chitin are examples of structural polysaccharides. Cellulose is used in the cell walls of plants and other organisms and is said to be the most abundant organic molecule on Earth.
Is dextran a Homopolymeric polysaccharide?
Dextran is a homopolymer of glucose produced by digesting amylopectin and can be readily produced via fermentation using yeast and bacteria (Fig. 13.5).
Is dextran isotonic?
Dextran is a complex branched glucan (polysaccharide made of many glucose molecules). When used as a component of colloid solutions, dextrans are mixed in normal saline as an isotonic solution.
Is dextran a colloid?
Dextrans are highly branched polysaccharide molecules which are available for use as an artificial colloid. They are produced by synthesis using the bacterial enzyme dextran sucrase from the bacterium Leuconostoc mesenteroides (B512 strain) which is growing in a sucrose medium.
What is the function of dextran?
Dextran is a medication used in managing and treating various clinical conditions, including during hemorrhage, shock, surgical procedures, radiological imaging, antithrombotic administration, and ophthalmic relief of xerophthalmia.
What is meant by dextran?
: any of numerous glucose biopolymers of variable molecular weight that are produced especially by the fermentation of sucrose by bacteria (such as genus Leuconostoc), are found in dental plaque, and are used especially in blood plasma substitutes.
What makes a dextran different from a dextrin chain?
Dextran chains are of varying lengths (from 3 to 2000 kilodaltons ). The polymer main chain consists of α-1,6 glycosidic linkages between glucose monomers, with branches from α-1,3 linkages. This characteristic branching distinguishes a dextran from a dextrin, which is a straight chain glucose polymer tethered by α-1,4 or α-1,6 linkages.
What is the molecular formula for dextran PubChem?
Dextran PubChem CID 4125253 Structure Find Similar Structures Molecular Formula C18H32O16 Synonyms DEXTRAN 9004-54-0 Dextran 40 Molecular Weight 504.4
How is dextran used in the medical field?
Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes. Dextran 70 is a plasma volume expander. Agents that prevent BLOOD CLOTTING. (See all compounds classified as Anticoagulants .)
How is dextran used as a plasma expander?
Dextrans, a group of polysaccharides composed of glucose, are secreted by certain strains of bacteria as slimes. The structure of an individual dextran varies with the strain of microorganism. Dextrans can be used as plasma expanders (substitutes for whole blood) in cases of severe shock.…