What is the use of piperazine?

What is the use of piperazine?

Piperazine belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections. Piperazine is used to treat: common roundworms (ascariasis) and.

Which of the following is example of piperazine?

Piperazine hydrate, piperazine adipate and piperazine citrate (used to treat ascariasis and enterobiasis) are the most common anthelmintic piperazine compounds.

What is the nature of piperazine?

Piperazine is a cyclic organic compound possessing two nitrogen atoms in opposite positions within a 6-member heterocyclic ring that serves as a backbone for piperazine derivatives and acts as a gamma-amino-butyric acid (GABA) receptor agonist in nematodes, with potential anti-helminthic activity.

Which drug is piperazine class?

Organic compound

What are the side effects of piperazine?

Side Effects

  • Blurring of vision.
  • clumsiness.
  • crawling or tingling feeling of the skin.
  • irregular, twisting movement, especially of the face, arms, and legs.
  • joint pain.
  • skin rash or itching.

Which drug is used to cure malaria?

Medications. The most common antimalarial drugs include: Chloroquine phosphate. Chloroquine is the preferred treatment for any parasite that is sensitive to the drug.

Is an example of piperazine derivatives Mcq?

Benzylpiperazine is the prototype of piperazine derivatives; this substance is the main component of recreational drugs, partly due to its stimulant and euphoric effects.

Which drugs contain piperazine ring?

Piperazine is a very popular motif in CNS drugs as shown in three atypical antipsychotics, one antidepressant, and one sedative hypnotic. Piperazine is also embedded in two tyrosine kinase inhibitors: imatinib (Gleevec™) and dasatinib (Sprycel™).

Is piperazine a secondary amine?

Piperazine, a secondary amine used as an anthelmintic drug, nitrosates rapidly in vitro to form two nitrosamines.

Is piperazine a tertiary amine?

The tertiary amine nitrogen atom of piperazine sulfonamides as a novel determinant of potent and selective beta3-adrenoceptor agonists. ChemMedChem.

Is piperazine a drug?

Piperazine is a medication used to treat roundworm and pinworm.

When was piperazine first used as a solvent?

First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953. Upon entry into the systemic circulation, the drug is partly oxidized and partly eliminated as an unchanged compound.

What is the name of the anthelmintic drug piperazine?

These drugs are often referred to simply as “piperazine” which may cause confusion between the specific anthelmintic drugs, the entire class of piperazine-containing compounds, and the compound itself. Diethylcarbamazine, a derivative of piperazine, is used to treat some types of filariasis .

What is the difference between piperidine and piperazine?

The -az- infix added to “piperazine” refers to the extra nitrogen atom, compared to piperidine. It is important to note, however, that piperazines are not derived from plants in the Piper genus .

How many nitrogen atoms are in a piperazine ring?

Piperazine is an azacycloalkane that consists of a six-membered ring containing two nitrogen atoms at opposite positions. It has a role as an anthelminthic drug.