What is Thiotepa injection for?
Thiotepa is used to treat certain types of ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed), breast, and bladder cancer. It is also used to treat malignant effusions (a condition when fluid collects in the lungs or around the heart) that are caused by cancerous tumors.
How long does docetaxel work for prostate?
Patients who had received 10 or more cycles of docetaxel had the greatest median OS of 33.0 months, compared with those who received 8 to 10 cycles (26.9 months) or 5-7 cycles (22.8 months) when treatment groups were combined (P < . 001) (Figure 2).
Does thiotepa cause hair loss?
Since the growth of normal body cells may also be affected by thiotepa, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects do not occur for months or years after the medicine is used.
What type of drug is thiotepa?
How long does docetaxel extend life?
Docetaxel is normally given after hormone treatment has failed. But results, to be presented at the American Society of Clinical Oncology, will show earlier treatment can extend life expectancy from 43 to 65 months.
How long does docetaxel work for?
The median overall survival (OS) was 81 months with docetaxel plus standard of care (hormonal therapy with or without radiotherapy) versus 71 months with standard of care alone (0.78; 95% CI, 0.66-0·93;P= . 006).
Does cyclophosphamide cause alopecia?
As an example, every-three-week, high- or moderate-dose, intravenous cyclophosphamide almost universally causes alopecia, while oral cyclophosphamide-containing regimens are less likely to do so. However, some weekly therapies cause grade 2 alopecia in most patients (eg, eribulin).
Does Cytoxan cause permanent hair loss?
Permanent alopecia, however, is rare after standard-dose therapy, but has occasionally been observed after high-dose chemotherapy with cyclophosphamide, thiotepa and carboplatin (CTC).
Does Taxotere prolong life?
First Evidence That Chemotherapy Extends Life in Advanced Prostate Cancer. Prostate cancer, docetaxel (Taxotere®), chemotherapy . (Definitions of many terms related to cancer can be found in the MedTerms Dictionary.)
Does Chemo extend life expectancy?
Chemotherapy (chemo) may prolong life in some lung cancer patients. According to a study reported in the Journal of the American Medical Association that looked at the role of chemotherapy at the end of life, chemo for some patients with a specific type of lung cancer prolonged their lives by two to three months.
How is thiotepa used in the treatment of cancer?
Thiotepa is also being studied in the treatment of other types of cancer and as part of a regimen to prepare patients for bone marrow and stem cell transplants. Definition from the NCI Drug Dictionary – Detailed scientific definition and other names for this drug.
Is it safe to give thiotepa to IV patients?
Thiotepa (also known as Thioplex ®) is an anticancer medicine. It is a clear liquid given by vein (IV). Thiotepa can pose a health hazard to caregivers. All caregivers should take safety precautions while giving this drug. For 48 hours after this drug is given, the patient’s body fluids can contain the drug.
How is chemotherapy used to treat prostate cancer?
How is chemotherapy given? Chemo drugs for prostate cancer are typically given into a vein (IV), either as an infusion over a certain period of time. This can be done in a doctor’s office, chemotherapy clinic, or in a hospital setting. Some drugs, such as estramustine, are given as a pill.
Where does thiotepa come from in the body?
Thiotepa can come through the skin as part of your sweat. You should try to protect the patient and caregivers from too much exposure to this drug. Follow these guidelines when the patient receives thiotepa, and keep following these guidelines for 24 hours after the last dose.